1st Faculty of Medicine Charles University 1st Faculty of Medicine Charles University Department of Occupational Medicine




Occupational diseases, Czech List of Occupational Diseases, European Schedule of Occupational Diseases, legislation, compensation.

Most frequent occupational diseases in the Czech Republic, duties of physicians concerning suspicion of the occupational origin of a disease, notification, social and economic impact. Endangerment with an occupational disease.

Occupational preventive care. Monitoring of the exposure to noxae in the occupational environment, biological exposure tests, preventive examinations of workers.

First aid in acute intoxications.

Antidotes for intoxications.

Intoxications with:

hydrogen cyanide and cyanides,

organic solvents (benzene, toluene, trichloroethylene, perchloroethylene, carbon tetrachloride, chloroform, ethyl alcohol, methanol, gasoline, ethylene glycol),

pharmaceuticals (paracetamol, benzodiazepins, morphine, tricyclic antidepressants) ,

metals (lead and its compounds, mercury and its compounds),

pesticides (organophosphates, carbamates, rodenticides),

carbon monoxide,

methemoglobinizing compounds,


Damage by acids and alkalis

Hepatotoxicity of chemicals - toxic liver damage, reversibility

Nephrotoxicity of chemicals – toxic kidney damage, reversibility

Occupational respiratory diseases:

occupational allergic diseases (allergic rhinitis, asthma, allergic skin diseases)

occupational interstitial fibroses (asbestosis, extrinsic allergic alveolitis)

silicosis and coal worker´s pneumoconiosis

diseases due to asbestos (benign diseases and tumours)

acute damage of the airways and lungs due to irritant gases, vapors and dusts

Occupational damage of the peripheral nerves (toxic, due to overload, vibrations-induced)

Disease due to vibrations

Diseases due to overload of upper extremities

Occupational carcinogens (chemical and physical), classification of carcinogens by IARC. Most common occupational carcinogens and their target organs.

Effects of ionizing radiation.

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